EZH2 immunoexpression in pleomorphic adenoma and adenoid cystic carcinoma and clinicopathological features
Braz. oral res. (Online)
;
38: e018, 2024. tab, graf
Artigo
em Inglês
|
LILACS-Express
| LILACS, BBO
| ID: biblio-1550152
ABSTRACT
Abstract The aim of this study was to evaluate the expression of the EZH2 protein and describe the clinical and microscopic characteristics of adenoid cystic carcinoma (ACC) and pleomorphic adenoma (PA). The study included 16 ACC cases and 12 PA. All ACC and PA cases were positive for EZH2 and the ACC samples showed significantly higher EZH2 expression. The clinical and microscopic covariates were described in relation to EZH2 staining in ACC samples. The highest mean values of EZH2 were observed in cases with local metastasis, recurrence, perineural invasion, and predominantly cribriform growth pattern without solid areas. EZH2 is a potential marker of malignancy.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Idioma:
Inglês
Revista:
Braz. oral res. (Online)
Assunto da revista:
Odontologia
Ano de publicação:
2024
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
/
Estados Unidos
Instituição/País de afiliação:
Universidade Federal de Goiás/BR
/
Universidade Federal de Minas Gerais/BR
/
University of Michigan/US
Similares
MEDLINE
...
LILACS
LIS