Mobile genetic elements related to carbapenem resistance in Acinetobacter baumannii
Braz. j. microbiol
;
47(4): 785-792, Oct.-Dec. 2016. tab
Artigo
em Inglês
| LILACS
| ID: biblio-828193
ABSTRACT
Abstract Acinetobacter baumannii is widely recognized as an important pathogen associated with nosocomial infections. The treatment of these infections is often difficult due to the acquisition of resistance genes. A. baumannii presents a high genetic plasticity which allows the accumulation of these resistance determinants leading to multidrug resistance. It is highlighted the importance of the horizontal transfer of resistance genes, through mobile genetic elements and its relationship with increased incidence of multidrug resistant A. baumannii in hospitals. Considering that resistance to carbapenems is very important from the clinical and epidemiological point of view, the aim of this article is to present an overview of the current knowledge about genetic elements related to carbapenem resistance in A. baumannii such as integrons, transposons, resistance islands and insertion sequences.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
DNA Bacteriano
/
Elementos de DNA Transponíveis
/
Carbapenêmicos
/
Resistência beta-Lactâmica
/
Acinetobacter baumannii
/
Antibacterianos
Idioma:
Inglês
Revista:
Braz. j. microbiol
Assunto da revista:
Microbiologia
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal do Rio Grande do Sul/BR
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