Behavior study of the doped castor bean polymer rod with bioactive glass and hidroxyapatite in mice femur medullary canal
Acta cir. bras
;
32(2): 116-124, Feb. 2017. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-837684
ABSTRACT
Abstract Purpose To evaluate the polymer doped rods behavior with bioactive glass and hydroxyapatite for possible application as a fracture fixing method. Methods Twenty eight Rattus norvegicus Wistar underwent bone defect for access to the femoral medullary canal and distributed into three experimental groups group A - doped castor bean polymer with bioactive glass; group B - castor bean polymer and; group C - castor bean polymer doped with bioactive glass and hydroxyapatite. After 15 and 60 evaluation days, the femurs were removed and sent for histology and scanning electron microscopy. Results Initially mild and moderate inflammatory infiltrate is observed that decreases as time goes by, and the presence of connective tissue capsule around the graft in all groups. Regarding the biomaterials resorption little was observed. The implanted rods did not favor the osteoconductive process in the femoral medullary canal which was observed only in the C15 group. Conclusions The association of castor bean polymer, bioactive glass and hydroxyapatite was biocompatible and osteointegrable. The osteoconductive only occurred in the presence of hydroxyapatite and bioactive glass (C15 Group) and little biodegradation was observed.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Materiais Biocompatíveis
/
Regeneração Óssea
/
Óleo de Rícino
/
Durapatita
/
Fêmur
/
Fixação Interna de Fraturas
/
Vidro
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de Mato Grosso do Sul/BR
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