Scleromyxedema: clinical diagnosis and autopsy findings
An. bras. dermatol
;
91(5,supl.1): 48-50, Sept.-Oct. 2016. graf
Artigo
em Inglês
| LILACS
| ID: biblio-837957
ABSTRACT
Abstract Scleromyxedema is a rare chronic cutaneous mucinosis of unknown etiology. It is characterized by papular eruption and scleroderma with microscopic evidence of mucin deposition, fibroblast proliferation, and fibrosis. Most patients with scleromyxedema have monoclonal gammopathy and systemic manifestations resulting in significant morbidity and mortality. Several types of treatment have been reported with partial or inconsistent responses. Despite showing unpredictable evolution, systemic consequences of scleromyxedema and treatment side effects may result in death. We describe a rare case of a patient with scleromyxedema without paraproteinemia with systemic involvement that evolved to death despite treatment with cyclophosphamide.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Pele
/
Escleromixedema
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Estadual de Campinas/BR
Similares
MEDLINE
...
LILACS
LIS