Angiosarcoma in HIV-negative patients is not associated with HHV-8
An. bras. dermatol
;
91(6): 738-741, Nov.-Dec. 2016. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-837975
ABSTRACT
Abstract: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Sarcoma de Kaposi
/
Neoplasias Cutâneas
/
Infecções Oportunistas Relacionadas com a AIDS
/
Soronegatividade para HIV
/
Herpesvirus Humano 8
/
Hemangiossarcoma
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR
Similares
MEDLINE
...
LILACS
LIS