Biopharmaceuticals from microorganisms: from production to purification
Braz. j. microbiol
;
47(supl.1): 51-63, Oct.-Dec. 2016. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-839328
ABSTRACT
ABSTRACT The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interferons (IFN α, β, and γ) and growth hormones. The production of biopharmaceuticals, known as bioprocess, involves a wide range of techniques. In this review, we discuss the technology involved in the bioprocess and describe the available strategies and main advances in microbial fermentation and purification process to obtain biopharmaceuticals.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Produtos Biológicos
/
Biotecnologia
/
Preparações Farmacêuticas
/
Técnicas Microbiológicas
Idioma:
Inglês
Revista:
Braz. j. microbiol
Assunto da revista:
Microbiologia
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de Sorocaba/BR
Similares
MEDLINE
...
LILACS
LIS