Adverse systemic reaction to benznidazole
Rev. Soc. Bras. Med. Trop
;
50(1): 145-147, Jan.-Feb. 2017. graf
Artigo
em Inglês
| LILACS
| ID: biblio-842820
ABSTRACT
Abstract Benznidazole, drug of choice for Chagas disease (CD), has been associated with a high incidence of adverse reactions that can become serious, necessitating discontinuation of the drug. We describe the case of a Bolivian patient living in Spain for 9 years, who, following treatment with benznidazole for CD in indeterminate chronic phase, presented with fever, skin lesions, digestive symptoms, general malaise, and laboratory abnormalities. After the discontinuation of benznidazole and, the intake of antihistamines and systemic corticosteroids, the patient presented a complete resolution of the symptoms. Optimization of dose strategies and development of more effective, and better-tolerated drugs is advisable.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Tripanossomicidas
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Nitroimidazóis
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Espanha
Instituição/País de afiliação:
Hospital Univesitari i Politècnic La Fe/ES
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