Introns in Cryptococcus
Mem. Inst. Oswaldo Cruz
;
113(7): e170519, 2018. graf
Artigo
em Inglês
| LILACS
| ID: biblio-894937
ABSTRACT
In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental cues. In addition, recent studies have revealed that C. neoformans introns help to prevent transposon dissemination and protect genome integrity. These characteristics of cryptococcal introns are probably not unique to Cryptococcus, and this yeast likely can be considered as a model for intron-related studies in fungi.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Criptococose
/
Cryptococcus neoformans
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
França
Instituição/País de afiliação:
Institut Pasteur/FR
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