Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome
Mem. Inst. Oswaldo Cruz
;
113(7): e180050, 2018.
Artigo
em Inglês
| LILACS
| ID: biblio-894943
ABSTRACT
Cryptococcosis diagnosis has been recently improved by the use of rapid cryptococcal antigen testing with lateral flow assays, which have proved sensitive and specific. Using "test and treat" screening strategies for cryptococcal disease with these tests has been showed effective in reducing cryptococcal meningitis (CM) in HIV-infected patients. Recommended induction, consolidation, and maintenance therapeutic strategy for CM is widely unavailable and/or expensive in low and middle-income settings. New therapeutic strategies, mostly using reduced duration, have recently shown acceptable outcome or are currently tested. Diagnostic and therapeutic guidelines for cryptococcal disease in limited resources countries are undergoing a paradigmatic shift.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Meningite Criptocócica
/
Infecções Oportunistas Relacionadas com a AIDS
/
Criptococose
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
Limite:
Humanos
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
França
Instituição/País de afiliação:
Institut Pasteur/FR
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