Sarcoma de Kaposi: variedades clínicas y resultados del tratamiento local con radioterapia / Local radiation treatment of Kaposi's sarcoma: clinical varieties and treatment outcomes
Rev. méd. Chile
;
146(1): 32-38, ene. 2018. tab
Artigo
em Espanhol
| LILACS
| ID: biblio-902619
ABSTRACT
Background: Kaposi's sarcoma (KS) is a rare tumor that affects mainly immunodeficient and elderly patients. Aim: To describe the features and outcomes of a cohort of patients with different types of KS treated locally with radiotherapy (RT). Patients and Methods: Retrospective review of patients with KS referred to our radiation oncology center for local treatment of symptomatic lesions that did not respond to high activity anti-retroviral therapy or chemotherapy. Results: Between January 1995 and December 2016, 20 patients with a median age of 40 years (18 males) with KS were assessed and treated with RT due to symptomatic lesions. The most common KS type was epidemic in 15 patients, followed by the classic type in three and the iatrogenic variety in two. In patients with non-epidemic varieties, SK was exclusively cutaneous, while visceral involvement was present in 46% of patients with epidemic SK. Complete response was observed in 95% of cases. Skin toxicity caused by RT was mild in all cases. Conclusions: RT may be considered as a reasonable local treatment choice in classic, iatrogenic and epidemic varieties of KS.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Sarcoma de Kaposi
/
Neoplasias Cutâneas
/
Fracionamento da Dose de Radiação
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Clínica Instituto de Radiomedicina/CL
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