Unmasking histoplasmosis immune reconstitution inflammatory syndrome in a patient recently started on antiretroviral therapy
Autops. Case Rep
;
6(4): 27-33, Oct.-Dec. 2016. ilus
Artigo
em Inglês
| LILACS
| ID: biblio-905080
ABSTRACT
Histoplasmosis is the most common endemic mycoses among HIV-infected people. Patients with suppressed cell immunity mainly due to HIV are at increased risk of disseminated disease. Dermatological manifestations of immune reconstitution inflammatory syndrome (IRIS) and cutaneous manifestations of histoplasmosis similar to an IRIS event have been previously described. We report the case of a 43-year-old male who presented with cutaneous disseminated histoplasmosis due to Histoplasma capsulatum var. capsulatum 4 months after the onset of the antiretroviral therapy and some improvement in the immune reconstitution. After 2 weeks of amphotericin B and itraconazole therapy, the scheduled treatment involved fluconazole maintenance therapy, which resulted in an improvement of his skin lesions.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Síndrome Inflamatória da Reconstituição Imune
/
Histoplasmose
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Autops. Case Rep
Assunto da revista:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Uganda
/
Estados Unidos
Instituição/País de afiliação:
Makerere University/UG
/
University of Minnesota/US
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