Perianal Langerhans cell histiocytosis: a rare presentation in an adult male
Autops. Case Rep
;
7(3): 38-43, July.-Sept. 2017. ilus, tab
Artigo
em Inglês
| LILACS
| ID: biblio-905320
ABSTRACT
Langerhans cell histiocytosis (LCH) is a rare disease characterized by a proliferation of cells that show immunophenotypic and ultrastructural similarities with antigen-presenting Langerhans cells of mucosal sites and skin. LCH in adults is rare, and there are still many undiagnosed/misdiagnosed patients. We describe LCH involvement of the perianal region of a 33-year-old male with a previous history of diabetes insipidus. The differential diagnosis and all the reported cases of LCH of the perianal skin involvement since its description in 1984 till 2016 are discussed. LCH should be considered in the differential diagnosis of perianal ulceration, especially in young patients where topical drug treatment has failed. The history of previous central diabetes insipidus of unknown etiology demands imaging studies in order to rule out central involvement of the disease.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Períneo
/
Histiocitose de Células de Langerhans
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Autops. Case Rep
Assunto da revista:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Egito
Instituição/País de afiliação:
Menoufia University/EG
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