Vitamin D levels in actinic keratosis: a preliminary study
An. bras. dermatol
;
93(4): 535-538, July-Aug. 2018. tab
Artigo
em Inglês
| LILACS
| ID: biblio-949908
ABSTRACT
Abstract Background:
Recent studies that investigated the effect of vitamin D on skin cancer risk have exhibited inconsistent results.Objective:
The aim of the study was to evaluate vitamin D status in patients with actinic keratosis.Methods:
A cross-sectional study was conducted on 31 patients with actinic keratosis and 29 healthy controls. Serum vitamin D levels in the study group were determined by liquid chromatography/tandem mass spectrometry.Results:
Serum 25(OH)D levels in patients with actinic keratosis were significantly higher than those of the healthy controls (P=0.04). Prevalence of 25(OH)D deficiency was significantly higher in the healthy controls (75.9%) compared to the patients with actinic keratosis (54.8%), but the difference was not statistically significant (P= 0.09). Studylimitations:
The cross-sectional design of the study, data on smoking based on patient self-report, and subjects' different dietary habits, which can influence 25(OH)D levels, are the study's limitations.Conclusion:
Serum vitamin D level can be used as a marker for ultraviolet B radiation from sun exposure; therefore, it can be used in individuals at risk of actinic keratosis. Oral intake of vitamin D through diet or supplements is proposed instead of prolonged ultraviolet exposure to maintain adequate vitamin D serum levels. Further research is needed to elucidate the role of vitamin D in skin carcinogenesis.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Vitamina D
/
Ceratose Actínica
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Bahçeşehir University/TR
/
Health Science University/TR
/
Medicalpark Bahçelievler Hospital/TR
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