Using mesenchymal stem cells as a therapy for bone regeneration and repairing
Biol. Res
;
48: 1-7, 2015. ilus
Artigo
em Inglês
| LILACS
| ID: biblio-950826
ABSTRACT
Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multiline-age potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of MSCs action in bone regeneration and repairing.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Osteogênese
/
Regeneração Óssea
/
Diferenciação Celular
/
Condrogênese
/
Transplante de Células-Tronco Mesenquimais
/
Células-Tronco Mesenquimais
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Biol. Res
Assunto da revista:
Biologia
Ano de publicação:
2015
Tipo de documento:
Artigo
País de afiliação:
China
Instituição/País de afiliação:
Second Military Medical University/CN
/
Shanghai Jiao Tong University/CN
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