Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
Braz. J. Pharm. Sci. (Online)
;
54(2): e17363, 2018. tab
Artigo
em Inglês
| LILACS
| ID: biblio-951923
ABSTRACT
ABSTRACT The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Crataegus
/
Hipóxia
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. J. Pharm. Sci. (Online)
Assunto da revista:
Farmacologia
/
Teraputica
/
Toxicologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Irã
Instituição/País de afiliação:
Golestan University of Medical Sciences/IR
/
Mazandaran University of Medical Sciences/IR
/
Tehran University of Medical Sciences/IR
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