Expression of Wnt and beta-catenin in mouse tooth germs and chick facial primordia: a comparison / Expresión de Wnt y beta-catenina en gérmenes de dientes de ratón y primordios faciales de polluelos: una comparación
Int. j. morphol
;
36(2): 569-575, jun. 2018. graf
Artigo
em Inglês
| LILACS
| ID: biblio-954156
ABSTRACT
In order to compare Wnt/ beta-catenin expression in mouse and chick facial primordia during development, we performed an immunohistochemical analysis of both protein expressions in E12 to E17 mouse embryos and in E3 and E10 chick embryos. During odontogenesis, from bud to bell stage, both proteins exhibit similar fixation patterns, with epithelial and mesenchymal immunoreactivity, consistant with literature data. Double labelling demonstrates that the same cells express both antigens, even in undifferentiated mesenchyme. The enamel knot, and the ameloblastic and odontoblastic layers are stained at the same manner. In the chick, Wnt and beta-catenin are diffusely present on craniofacial mesenchyme. In both species, premuscular blastemata express Wnt and b-catenin, but Wnt is specifically expressed on the perichondrium and ossification centers, suggesting a role independent from beta-catenin pathway.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Dente
/
Embrião não Mamífero
/
Proteínas Wnt
/
Beta Catenina
Limite:
Animais
Idioma:
Inglês
Revista:
Int. j. morphol
Assunto da revista:
Anatomia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Bélgica
Instituição/País de afiliação:
Université Libre de Bruxelles/BE
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