Influence of tramadol on functional recovery of acute spinal cord injury in rats
Acta cir. bras
;
33(12): 1087-1094, Dec. 2018. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-973483
ABSTRACT
Abstract Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a laminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn't receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don't influence on functional recovery of acute spinal cord injury in rats
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Traumatismos da Medula Espinal
/
Tramadol
/
Recuperação de Função Fisiológica
/
Analgésicos Opioides
Tipo de estudo:
Estudos de avaliação
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
CESUPA/BR
/
Centro Universitário do Estado do Pará/BR
/
UEPA/BR
/
UFRA/BR
/
Universidade Federal Rural da Amazônia/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR
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