Adipose tissue is less responsive to food restriction anti-inflammatory effects than liver, muscle, and brain in mice
Braz. j. med. biol. res
;
52(1): e8150, 2019. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-974270
ABSTRACT
High caloric intake promotes chronic inflammation, insulin resistance, and chronic diseases such as type-2 diabetes, which may be prevented by food restriction (FR). The effect of FR on expression of pro-inflammatory and anti-inflammatory genes in adipose tissue, liver, muscle, and brain was compared. Male Swiss mice were submitted to FR (FR group) or had free access to food (control group) during 56 days. The liver, gastrocnemius muscle, brain, and epididymal white adipose tissue (WAT) were collected for analysis of gene expressions. FR attenuated inflammation in the liver, brain, and gastrocnemius muscle but did not markedly change inflammatory gene expression in epididymal WAT. We concluded that adipose tissue was less responsive to FR in terms of gene expression of pro-inflammatory and anti-inflammatory genes.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Encéfalo
/
Tecido Adiposo
/
Músculo Esquelético
/
Dieta Hiperlipídica
/
Fígado
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Cruzeiro do Sul/BR
/
Universidade Estadual de Maringá/BR
/
Universidade Federal do Paraná/BR
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