Ameloblastoma with distinctive granular cell pattern: an 8 case study
Autops. Case Rep
;
8(4): e2018052, Oct.-Dec. 2018. ilus
Artigo
em Inglês
| LILACS
| ID: biblio-986609
ABSTRACT
Ameloblastoma with granular cell pattern (AGC) is classified as an unusual histological subtype of solid/multicystic ameloblastoma, characterized by granular changes in stellate-like cells located within the inner portion of the epithelial follicles. Studies have revealed that lysosomal overload causes cytoplasmic granularity; however, the mechanism involved remains poorly understood. Here we report on eight cases of granular cell ameloblastoma, in the posterior region of the mandible. The age of the patients included in this case series ranged from 35 -64 years old and 87.5% of cases occurred in non-Caucasians, with a slight gender predilection for men (62.5%). There was no evidence of recurrence, and the majority of the cases were treated with surgical resection (87.5%). All tumors displayed histopathological features consistent with the diagnosis of ameloblastoma with granular cell pattern.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Ameloblastoma
/
Neoplasias Maxilomandibulares
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Autops. Case Rep
Assunto da revista:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
AC Camargo Cancer Center/BR
/
Universidade de São Paulo/BR
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