Isoniazid-resistant tuberculous spondylodiscitis associated with scrofuloderma
Rev. patol. trop
;
47(4): 247-253, dez. 2018. ilus
Artigo
em Inglês
| LILACS
| ID: biblio-996645
ABSTRACT
The extrapulmonary forms of tuberculosis are responsible for about 20% of cases. Scrofuloderma is the cutaneous manifestation secondary to infection in some subcutaneous foci. A 33-year-old patient was admitted to the Clinical Hospital with exudative skin lesions on the back and thorax, initiated 10 months previously, associated with daily fever, and constipation. Spine resonance showed a paravertebral pseudotumoral lesion with T4 and T9 invasion, including vertebral canal and sub-ligament extension. The lesions presented fistulas for paravertebral muscles, lung and skin. Polimerase chain reaction (PCR) proved positive for Mycobacterium tubeculosis in the thorax wound secretion, caracterizing tuberculous spondilodiscitis with scrofuloderma. Treatment was initiated with rifampicin, isoniazid, pyrazinamide and ethambutol with important clinical improvement after the first week. The febrile peaks came to an end and there was improvement in the pattern of the cutaneous lesions. The susceptibility test showed resistance to isoniazid
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Traumatismos Torácicos
/
Tuberculose Cutânea
/
Discite
/
Mycobacterium tuberculosis
Tipo de estudo:
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. patol. trop
Assunto da revista:
Medicina Tropical
/
Patologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Hospital das Clínicas, UFG/BR
/
Institute of Tropical Pathology and Public Health, Federal University of Goiás (UFG)/BR
/
Institute of Tropical Pathology and Public Health, Federal University of Goiás (UFG/BR
/
Tropical Diseases Hospital Dr Anuar Auad/BR
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