[Comparison effect of different doses of Ketamine with Pethedine in reducing postoperative shivering after cesarean section]

ABSTRACT

Postoperative shivering is a common problem with multiple complications. This study was compared effect of low doses of Ketamine with Pethidine for controlling postoperative shivering. This clinical trial was done on 189 elective cesarean section with ASA class I or II who had postoperative shivering. Patients with grade 2 or higher were divided in three groups and were injected 0.3mg/kg Ketamine and 0.5mg/kg Pethidine intravenously. In 5[th] and 10[th] minutes after injection, they were investigated for shivering intensity. After 5 minute of injection drugs rate and intensity of shivering in Pethedine group was less than Ketamine group. Ketamine with 0.5 mg/kg was more effective than 0.3mg/kg dose of it and Ketamine[p=0.041]. In group with 0.5mg/kg dose of Ketamine, rate and intensity of postoperative shivering was more reduce than group with 0.3mg/kg of it in recovery [p=0/007]. In Pethedine group rate and intensity of shivering was more reduce then 0.5mg/kg dose of Ketamine[p<0/001]. This demonstrated that Pethedine is more effective than Ketamine. Although 0.5mg/kg dose of Ketamine has considerable effect on control of shivering but Pethedine is still a better choice for this side effect