Evaluation of the role of thrombophilia associated factors in pre-eclampsia
Bulletin of Alexandria Faculty of Medicine. 2008; 44 (3): 621-625
em Inglês
| IMEMR
| ID: emr-101649
ABSTRACT
To evaluate the role of thrombophilia associated factors in pre-eclamptic pregnant women. A case control study was conducted on 30 severe pre-eclamptic pregnant women [group A], and 30 normotensive pregnant women [group B] from Shatby University Maternity Hospital. Routine laboratory tests, protein C, protein S, antithrombin III, factor V Leiden and anticardiolipin antibodies [IgM, IgG] were measured for both groups. Informed consent of the patients was taken. There was not any significant difference in the values of factor V Leiden, protein C, protein S, antithrombin III, and anticardiolipin IgG between pre-eclamptic and normotensive pregnant women. However, anticardiolipin IgM was shown to be significantly higher in the pre-eclamptic patients. Severe pre-eclamptic patients were 3.5 times more likely to develop elevated levels of anticardiolipin IgM. Routine screening for inherited thrombophilia disorders is not recommended in pre-eclamptic females
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Feminino
/
Proteína C
/
Antitrombina III
/
Proteína S
/
Anticorpos Anticardiolipina
/
Trombofilia
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Bull. Alex. Fac. Med.
Ano de publicação:
2008
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