[ survey of administration of cherries ethanolic extract on the serum levels of lipids of diabetic rats]

ABSTRACT

Diabetes mellitus is a metabolic disorder in the endocrine system resulting from a defect in insulin secretion, insulin action or both. It is the most common endocrine disorder and by the year 2010, it is estimated that more than 200 million people worldwide will have DM and 300 million will subsequently have the disease by 2025. Tart cherry [Rosaceae] are packed with powerful plant pigments called anthocyanins-which give cherries their dark red color-and it's these compounds one of richest antioxidant sources, lower blood sugar and insulin levels. Adding cherries to the diet also lower the animals' total cholesterol levels and triglycerides. The present study was designed to investigate the effect of Cherries Ethanolic Extract on the Serum Levels of Lipids on Alloxan induced diabetic rats. In this study 36 Male Wistar rats, body weight of 150-200 gr were divided into 6 groups. Diabetes was induced by intra peritoneal injection of 120 mg/kg Alloxan. The duration of the cherries treatment was 30 days. Treatment with extracts of cherries resulted in a significant reduction in triglyceride, LDL, as well as increase in HDL level. Extracts from this plant useful in controlling blood lipids levels. Cherries appear to aid in diabetes control and in reducing the complications of disease