Intensive insulin therapy versus conventional insulin therapy for critically ill trauma patients admitted to ICU
Middle East Journal of Anesthesiology. 2010; 20 (5): 659-666
em Inglês
| IMEMR
| ID: emr-105621
ABSTRACT
The objective of our study was to evaluate the beneficial effect of IIT in reducing mortality and morbidity in critically ill trauma patients admitted to ICU. Nested cohort study within a Randomized Controlled Trial. All trauma patients with GCS = 9 included in the original trial were included in this study. Primary outcome was ICU mortality. There was no difference in ICU mortality between IIT and CIT groups [6.5% vs. 5.5%, p=0.67]. After adjustment for baseline characteristics, IIT therapy was also not associated with mortality [Adjusted Hazard Ratio 1.33, 95% CI 0.35-5.05]. IIT therapy was associated with a significant increase in the incidence of hypoglycemia as compared to CIT, at least one hypoglycemia episode occurred in 18.5% of patients in IIT and 1.3% in the CIT group [P<0.0001]. IIT was not associated with survival improvement in trauma patients admitted to ICU and was associated with increased incidence of hypoglycemia
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Ferimentos e Lesões
/
Traumatismo Múltiplo
/
Estudos de Coortes
/
Mortalidade
/
Resultado do Tratamento
/
Estado Terminal
/
Sepse
/
Convulsoterapia
/
Coma Pós-Traumatismo da Cabeça
/
Hipoglicemia
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de incidência
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Middle East J. Anesthesiol.
Ano de publicação:
2010
Similares
MEDLINE
...
LILACS
LIS