Stage I and II seminoma of the testa, KFSH experience

ABSTRACT

The registry of the radiotherapy department of the King Faisal Specialist Hospital and Research Center [KFSH] reported 60 patients of stages I and II seminoma of the testis. The age of the patients ranged 19-78 years with a median of 37 years. 40 patients presented in stage I and 20 in stage II. The 5-year actuarial disease free survival for stage I patients was 100% compared with 50% for stage II patients. Different prognostic parameters were studied including the treatment modality, elevated HCG level, cryptorchidism and the substage of the disease. All the studied prognostic factors did not seem to influence the survival rate except the treatment modality. Stage II group included one patient with stage IIa, 7 with stage IIb and 12 with stage IIc. There was no difference in survival between stage IIa + IIb and stage IIc. 10 patients in stage II were treated with radiation therapy alone and 10 received chemotherapy as well. The 5-year actuarial disease free survival for the radiation alone group was 21% compared with 100% for the chemoradiotherapy group