Medulloblastoma results of treatment of 45 patients

ABSTRACT

This study dealt with characteristics and treatment outcome of 51 patients with medulloblastoma [27 females and 24 males]. According to the Chang staging system, four patients had T1, 15 had T2, 13 had T3 and 16 had T4 tumors and the stage was unknown in three patients. Eight patients had leptomeningeal dissemination [M3]. Complete tumor resection was performed in 12, near total resection in nine, partial resection in 19 and biopsy only in 11 patients. Forty-five patients completed postoperative irradiation using a telecobalt machine with an 80 cm SSD. The total dose to the whole brain ranged from 30-40 Gy over 4-5 weeks and an additional boost of 15-20 Gy over 2-3 weeks was given to the posterior fossa. The total dose to the spinal cord ranged from 30-35 Gy over 4-5 weeks