Parathormone, calcitonin and osteocalcin in chronic renal failure with and without schistosomiasis

ABSTRACT

The present study was conducted on 28 male patients suffering from chronic renal failure aged from 20-40 years, 16 of them were bilharzial and 12 were non bilharzial. Healthy 14 males matching for age were selected as control, 8 of them were bilharzial and 6 were non bilharzial. Serum parathormone, calcitonin and osteocalcin levels were estimated. Serum levels of parathormone and osteocalcin showed significant increase in uremic patients while calcitonin level showed insignificant changes. On the other hand, parathormone, osteocalcin and calcitonin levels in chronic renal failure on top of schistosomal infestation showed insignificant results. It is concluded that the significant increased levels of parathormone and osteocalcin in chronic renal failure can be attributed to disturbance in renal functions due to chronic renal failure