Platelet screening tests in patients with hepatic cirrhosis

ABSTRACT

This is the largest report to investigate the importance of platelet screening tests in patients with hepatic cirrhosis. One hundred eighty seven patients were examined in this study. On an appropriate clinical historic back ground, biochemical results and biopsy - proven cirrhotic patients were investigated. An abnormal bleeding time was found in 78 patients. There were significant differences between the group of patients with an abnormal bleeding time and the group with a normal bleeding time with respect to platelet count, prothrombin time and serum bilirubin concentrations [all p < 0.05]. We recommend to measure the bleeding time in patients with raised bilirubin concentrations or poor hepatic function, even if platelet counts and prothrombin time are with in [safe limits], before making a decision about potentially dangerous therapeutic measures, such as surgery