Glucose tolerance and insulin response in myocardial infarction patients in type 2 diabetes mellitus

ABSTRACT

To investigate glucose tolerance and insulin response in myocardial infarction patients in type-2 diabetic population, normoglycemic FDRs or type-2 DM patients and MI with out DM and having no history of type-2 DM in family. Sixty five MI patients and twenty two healthy controls were selected for study. Subjects were divided in to four groups. The study was conducted for the period of 9 months in cardiology ward of various hospitals. Fasting plasma glucose levels in diabetic patients were abnormally higher as compared to other groups. Mean insulin level of FDRs and diabetic MI patients were significantly higher than controls and non diabetics. When viewed with higher fasting glucose level in groups, indicates considerable resistance. Higher insulin levels of FDRs may indicate start of insulin resistance at normoglycemic control. Finally we conclude that insulin resistance appears to be risk factors in diabetics and FDRs MI groups, while in non diabetics, non FDRs, MI patients these risk factors does not seem to play major role