Piebaldism and vitiligo in two brothers

ABSTRACT

Piebaldism is an autosomal dominant uncommon [<1 in 20,000] congenital pigmentary disorder. Depigmented patches are present since birth. They usually remain unchanged throughout life. Vitiligo is its closest differential diagnosis. We report a unique family in which these two dissimilar depigmentations, i.e. piebaldism and vitiligo [with nevus depigmentosus], were noted in two brothers. To the best of our knowledge, this is the first report of this presentation in the literature