Neuro-ophthalmological symptoms [lisch nodules], in neurofibromatosis type 1 [NF1]

ABSTRACT

Neurofibromatosis type 1 [NF1] is a genetic disorder where the affected persons can have cutaneous tumors prominently, and other features that affect the persons health and self-esteem. The Lisch nodules are haematomas in the iris of the NF1 patients is one of the ophthalmologic symptoms. The severity of the NF1 symptoms can influence one's life dissatisfactions. It was found that the complication occurred due to severity of Lisch nodules in the eyes, affects vision and severe photophobia. Lisch nodules appear in both the eyes are progressive with age, cause aggressiveness, irritation and unbearable upset in life. Patients were recruited by invitation and visit undertaken to their places through [NMNF] Nazar Muhammad Neurofibromatosis Foundation, it was a family on follow-up study