High altitude pulmonary oedema - response to exercise and cold on systemic and pulmonary vascular beds
JPMA-Journal of Pakistan Medical Association. 1988; 38 (8): 211-217
em Inglês
| IMEMR
| ID: emr-10985
ABSTRACT
Fourteen subjects who were acclimatised to a height of 7000 feet [average duration 3 +/- months] were investigated. Five were normal subjects [Group I] and 9 were those who developed high altitude pulmonary oedema [Group 2]. At the National Institute of Heart Diseases, Rawalpindi, clinical examination, chest X-ray, electrocardiogram, haematological tests, thyroid functions, echocardiography and lung function tests were normal. During exercise testing the blood pressure response was exaggerated in Group 2 compared to Group 1 [P < 0.01]. Cardiac catheterisation revealed no significant difference in the intracardiac pressures in the resting state in the two groups [P = NS]. With cold pressor test the pulmonary pressure and aortic pressure rose significantly in Group 2 as compared to Group 1 [P < 0.01]. It is suggested, therefore, that pulmonary and systemic vascular beds are hyper-responsive to cold in the susceptible subjects [Group 2]. This phenomenon may be further aggravated by exertion, hypoxia, and other undetermined factors in producing pulmonary oedema
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Temperatura Baixa
/
Teste de Esforço
/
Altitude
Idioma:
Inglês
Revista:
J. Pak. Med. Assoc.
Ano de publicação:
1988
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