AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chemotherapy regimen and high active antiretroviral therapy
Hematology, Oncology and Stem Cell Therapy. 2011; 4 (1): 41-44
em Inglês
| IMEMR
| ID: emr-110146
ABSTRACT
Burkitt lymphoma [BL] is the second most common AIDS-related lymphoma. Primary sinonasal BL in HIV patients is extremely rare and treatment data in this subset of patients is almost nonexistent. Recently, a few studies reported promising results treating HIV-associate BL with an intensive chemotherapy regimen. The use of highly active antiretroviral therapy [HAART] concomitantly with chemotherapy seems to improve patient outcomes, but this topic is still controversial due to potential drug interactions. We report a case of a 29-year old woman diagnosed with AIDS presenting with symptoms of chronic sinusitis. Subsequent investigation by CT scan and endoscopic biopsy discovered a sinonasal BL in an early stage. The patient was treated with intensive chemotherapy and HAART and achieved a complete remission and long-term immunologic recovery. This case report describes a rare entity whose natural history, treatment and prognosis is infrequently characterized in the medical literature
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
/
Taxa de Sobrevida
/
Resultado do Tratamento
/
Linfoma Relacionado a AIDS
/
Terapia Antirretroviral de Alta Atividade
Tipo de estudo:
Relato de Casos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Hematol. Oncol. Stem Cell Ther.
Ano de publicação:
2011
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