La maladie de cowden: a propos du premier cas Marocain

Described by LIOYD and DENNIS in 1963, Cowden's disease is a familial affection in which are found associated lesions of the buccopharyngeal mucosa [papillomatosis, papules, scrotal tongue], various types of skin lesions [verruciform keratotic papules, papilloma, lipoma, angioma etc.], visceral manifestations usually related to lesions in the thyroid, breasts, or digestive tract [hamartoma or malignant tumors], and skeletal dysmorphism. Our patient wase aged 14 years, and had presented for consultation because of buccal mucos membrane papillomatosis. Cowden's disease was diagnosed from the clinical examination, past history, and investigations after hospital admission. The main value of the mucosal and cutaneous lesions is their diagnostic significance, enabling a synthesis of the multiple dispersed manifestations to be made, and a possible visceral tumor to be discovered in the early stages