Evaluation of cytomegalovirus infection after six months of liver transplantation in children in Shiraz, Southern Iran
International Journal of Organ Transplantation Medicine. 2011; 2 (1): 20-23
em Inglês
| IMEMR
| ID: emr-110837
ABSTRACT
Liver transplantation [LT] is a life-saving treatment for end-stage liver diseases [ESLD]. Cytomegalovirus [CMV] infection is one of the important causes of morbidity after LT. To evaluate the incidence of late-onset [after 6 months of LT] CMV infection in pediatric recipients. A retrospective analysis was conducted to evaluate 50 pediatric patients who underwent LT for 8 years at the LT Unit of Nemazee Hospital affiliated to Shiraz University of Medical Sciences, Shiraz, Iran. We retrospectively investigated episodes of CMV infection after 6 months of LT proven by CMV antigenemia test. Three recipients [6%] developed late-onset CMV infection. These patients finally responded to ganciclovir. CMV infection is one of the most common post-LT viral infections that usually occurs in the first six months of LT. Our study shows that the incidence of late-onset CMV infection is relatively low, but it still remains a significant problem. Therefore, monitoring and management is crucial for improving the survival of children
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Ganciclovir
/
Criança
/
Estudos Transversais
/
Estudos Retrospectivos
/
Transplante de Fígado
/
Citomegalovirus
/
Doença Hepática Terminal
Tipo de estudo:
Estudo de prevalência
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. J. Organ Transplant. Med.
Ano de publicação:
2011
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