Effect of green tea, curcumin and ginger extracts and its combination on liver and kidney functions in rats after carbon tetrachioride exposure

Oxidative stress is a major factor in the pathogenesis of diabetic complications. We studied the effects of green tea, curcumin and ginger extracts or its combinations on the kidney and liver function for rats exposure to CCL[4] injection. The results indicated that, all treated groups with low and high concentrations of ginger extract had uric acid and urea nitrogen lower than untreated group [control positive groups]. Moreover green tea had the most significant protection for kidney function against CCI[4]. In additional, there was a significant difference in serum glucose level between the low [10 gm] and high [20 gm] concentration of each individual herb or herbal combinations. The high concentration of the herb or its combinations resulted in a significantly lower serum AST and ALT levels than the low herbal concentration. But, all investigated herbs had significant protection for liver function against CCI[4]. It was concluded that, concurrent treatment of investigated herbs extract gave significant protection against CCI[4] though the values did not reach the normal levels