Detection of carcinoembryonic antigen [CEA] in breast cancer tissue and it's relation to some prognostic histological features

ABSTRACT

Carcinoembryonic antigen was searched for in tissue sections from 34 radial mastectomy specimens with breast carcinoma. These sections were stained using unlabelled peroxidase-antiperoxidase technique and polyvalent rabbit antiserum to CEA. The positivity of CEA staining in carcinoma cells was 44.11 percent of the total. Correlating this to the histological type and grading of tumour, lymphoid infiltrate in tumour bed and the auxillary lymph nodes metastases, no clear significant relation was detected between them