Significance of hepatitis B virus antibodies in Saudi patients with chronic hepatitis C infection
Saudi Medical Journal. 1997; 18 (1): 42-4
em Inglês
| IMEMR
| ID: emr-114674
ABSTRACT
To study the clinical significance of antibodies to hepatitis B virus among 100 Saudi patients with chronic hepatitis C virus infection. The records of 100 patients with hepatitis C virus [HCV] infection who were admitted between November 1990 and January 1994 were retrospectively studied. These patients were classified into 3 groups according to their serological hepatitis B virus [HBV] status. Group one comprised of 43 patients lacking in HBV antibody and serving as controls. Twenty-nine patients in Group two were positive for HBcAb only, while Group three included 28 patients positive for both HBcAb and HBsAb. Patients with hepatitis C infection who had hepatitis B core antibodies [HBcAb] or both HBcAb and hepatitis B surface antibodies [ABsAb] were more likely to be cirrhotic as compared to sex and age, matched controls lacking antibodies to HBV [75.8%] and 80% respectively vs 48.5%]. When present, cirrhosis was more likely to be decompensated in patients with HBV antibodies as compared to controls [36% and 37.5%] vs 0% Child-Pugh's grade C. Number of hepatocellular carcinomas [HCC] appeared to be related to that of cirrhosis [28% and 34% vs 31% in controls]. It is concluded that patients with chronic hepatitis C virus infection have more severe liver disease when they have been previously infected by hepatitis B virus
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Doença Crônica
/
Carcinoma Hepatocelular
/
Anticorpos Anti-Hepatite B
/
Cirrose Hepática
Limite:
Humanos
Idioma:
Inglês
Revista:
Saudi Med. J.
Ano de publicação:
1997
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