JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 1998; 8 (3): 106-109
em Inglês
| IMEMR
| ID: emr-115389
ABSTRACT
The effects of verapamil on naloxone precipitated effects of morphine-dependent guinea pigs ileum were studied in vitro. Dependence was produced in experimental animals by repeated administration of morphine for 15 days. Non-dependent animals given saline for the same period were taken as controls. Verapamil effectively blocked the naloxone induced contractions in ileal strips of morphine-dependent animals. These observations on animal tissues are significant and may suggest clinical usefulness of verapamil in the management of morphine-dependent patients
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Verapamil
/
Cobaias
/
Íleo
/
Dependência de Morfina
/
Naloxona
Limite:
Animais
Idioma:
Inglês
Revista:
J. Coll. Physicians Surg. Pak.
Ano de publicação:
1998
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