electrophoretic pattern of serum proteins in chickens vaccinated with newcastle [different strains and gumboro vaccines

ABSTRACT

The present work was planned to study the effect of vaccination with different strains of Newcastle disease virus vaccine [NDVV] as well as vaccination with Gumboro vaccine on the electrophoretic pattern of serum proteins in our local breed [Baladi]. One hundred and fifty three one day old chicks were used. Our results revealed that there was a significant increase in the levels of total serum proteins, albumin, total globulins and gamma-globulin in the sera of chickens vaccinated with NDVV whereas there was no significant difference between Gumboro vaccinated chickens and control group in the total serum proteins and its fractions. The chickens vaccinated with komarov strain of NDVV showed the highest mean values of total serum proteins, albumin, total globulins and gamma-globulin whereas the lowest values were observed in the chickens vaccinated with Gumboro and Lasota strain of NDVV. Concerning the type of vaccine and weeks post-vaccination. The mean values of total serum proteins, albumin, total globulins and beta-globulins were significantly increased in chickens vaccinated with NDVV either with komarov or Lasota strains at the 1st week post-vaccination. In the 2nd week post-vaccination, the mean values of beta-globulin fraction in group vaccinated with NDVV and chickens vaccinated with NDVV [without last dose] and Gumboro vaccine was significantly decreased. Furthermore, the total serum proteins were significantly decreased in chickens vaccinated with Gumboro and NDVV [K]. In the 3rd week post-vaccinated with Gumboro [L]. It was concluded that the vaccination of chicks with Gumboro vaccine at 14 day of age delay the response of immune system for vaccination with Newcastle disease virus vaccine [NDVV]