Value of C reactive protein determination in bacterial meningitis

This work was carried out on 20 patients with bacterial meningitis in a trial to investigate the value of C reactive protein [CRP] in serum and CSF as a diagnostic and prognosis index in sush disease. Before therapy CRP in serum and CSF was significantly high seven days from the start of therapy CRP dropped significantly in 95% of cases only one patient [5%] who developed facial nerve palsy showed elevated CRP. Therefore early determination of CRP in serum and CSF may be a sensitive and rapid indicator of bacterial meningitis and also may have a prognostic value as it decreases markedly when there is recovery