Hysteroscopically directed endometrial biopsy versus full endometrial curettage in perimenopausal bleeding

ABSTRACT

Hysteroscopically guided biopsy was evaluated versus full curettage biopsy in 50 patients presented with perimenopausal bleeding. The presenting symptom was metrorrhagia in 58%, menometrorrhagia in 24% and menorrhagia in 18% of cases. Two specimens of the hysteroscopic directed biopsies were unfit for histopathologic examination Endometrial hyperplasia was diagnosed in 66% of the hysteroscopic biopsies and 74% of the full curettage biopsies. The overall diagnostic efficacy of hysteroscopic biopsy in diagnosing endometrial pathology was 84% for simple endometrial hyperplasia 92% for cystic endome trial hyperplasia, 96% for regressive hyperplasia, and 88% for proliferative endometrium. There was an agreement between the two procedures in 76% of cases. Hysteroscopy revealed more informations in 24% of cases