Insulin response and carbohydrate tolerance among Egyptian hypertensive patients

ABSTRACT

This study was conducted on 15 hypertensive patients and 1 0 normal control subjects, in order to study the insulin response and carbohydrate tolerance among them. All the hypertesive patients stopped their anti-hypertensive drugs one week before the study. The patients and controls were matched for age sex and body mass index They were non diabetic and non smoker. The results of the study showed significantly higher both fasting and postprandial plasma glucose and serum insulin levels among the hypertensive patients than the controls and there was a significant positive correlation between plasma glucose and serum insulin levels among hypertensive patients indicating insulin resistant state. There was also significant positive correlation between both systolic and diastolic blood pressures with fasting plasma glucose and serum insulin levels