Effects of garlic [allium sativum] administration on: 1-serum lipids, lipoproteins and some physiological parameters in healthy male subjects

ABSTRACT

Garlic has been claimed to be effective against many diseases, a daily ingestion of 4-5 fresh garlic cloves were given to 14 healthy male volunteers along 30 days. Eight healthy male volunteers were served as control, their ages ranged [35-50 years], to evaluate the effects of garlic use on serum total lipids, lipoprotein cholesterol fractions and ratios, cortisol, glucose and liver transaminase enzymes. Garlic consumption produced significant reduction in total lipids, total cholesterol and T-ch/HDL-C ratio, significant increase in HDL-C. No differences in serum triglycrides, LDL-C, HDL C/LDL-C, cortisol, glucose and SOOT, SGPT liver enzymes were observed in comparison to control or before garlic ingestion. The results suggest that garlic may be of some use as lipid lowering agent, hypocholeslerolaemic action and anti-atherosclerosis-related effects