International Journal of Diabetes Mellitus. 2010; 2 (2): 125-126
em Inglês
| IMEMR
| ID: emr-117856
ABSTRACT
Glucose filtered by kidneys is reabsorbed into the proximal tubule through the sodium-coupled glucose co-transporter [GLT2] This promotes urinary excretion of glucose and results in lowering of plasma glucose level. Administration of agents [.g. dapagliflozin] hat inhibits SGLT2 transporter have shown to be associated with improvement in hyperglycaemia without clinically persistent electrolytes disturbances or change in osmolarity. This may suggest that administration of dapagliflozin is effective and safe as treatment for hyperglycaemia. Ongoing clinical trials will reveal the potential benefit and safety of SGLT2 inhibitors as part of the therapy of type 2 diabetes
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Diabetes Mellitus
/
Proteínas de Transporte de Sódio-Glucose
/
Rim
Idioma:
Inglês
Revista:
Int. J. Diabetes Mellitus
Ano de publicação:
2010
Similares
MEDLINE
...
LILACS
LIS