[Anti-inflammatory effect of capparis spinosa in experimental animals]
Arab Journal of Pharmaceutical Sciences. 2010; 4 (3): 45-51
em Inglês, Árabe
| IMEMR
| ID: emr-117886
ABSTRACT
The effects of both the aqueous and methanol extracts of Capparis spinosa on inflammation were investigated. Anti-inflammatory effect was evaluated by carrageenan-induced rat paw oedema method. The change in oedema volume of the rat hind paw was measured using caliper. Tow extracts have shown dose-dependent anti-inflammatory effect and dexamethasone [0.5 mg/Kg] was used as a standard drug. The aqueous extract was more potent than methanolic with tow doses 250 and 500 mg/Kg. These data indicate that anti-inflammatory efficacy depends on concentrations of effective compounds in plant extracts which affect mediators of inflammation
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Ratos
/
Extratos Vegetais
/
Carragenina
/
Modelos Animais de Doenças
/
Edema
/
Anti-Inflamatórios
Limite:
Animais
Idioma:
Árabe
/
Inglês
Revista:
Arab J. Pharm. Sci.
Ano de publicação:
2010
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