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JPAD-Journal of Pakistan Association of Dermatologists. 2010; 20 (4): 246-248
em Inglês | IMEMR | ID: emr-117935
ABSTRACT
Sclerosing panniculitis is a fibrotic process that usually occurs on the legs, commonly in women older than 40. The principal features are indurated woody plaques with erythema, edema, telangiectasia, and hyperpigmentation. Although the exact pathogenesis is uncertain, it is thought to occur as a result of ischemic changes. We present a 28-year-old married female who had a 10-year history of painful sclerotic plaques, repeated ulceration and healing with fibrosis of the both lower legs and abdomen. Venogram and Doppler investigations were normal. Skin biopsy from the edge of the ulcer demonstrated the feature of chronic sclerosing panniculitis. Satisfactory improvement was found with methotrexate 7.5mg weekly for 4 months. No recurrence was noted within 1 year follow up
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Esclerodermia Localizada / Paniculite / Metotrexato / Dermatite Tipo de estudo: Relato de Casos Limite: Feminino / Humanos Idioma: Inglês Revista: J. Pak. Assoc. Dermatol. Ano de publicação: 2010

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Esclerodermia Localizada / Paniculite / Metotrexato / Dermatite Tipo de estudo: Relato de Casos Limite: Feminino / Humanos Idioma: Inglês Revista: J. Pak. Assoc. Dermatol. Ano de publicação: 2010