association between oral lichen planus and HCV infection

ABSTRACT

The purpose of this study was to investigate the possible epidemiological relationship between Oral Lichen Planus [OLP] and Hepatitis C Virus [HCV] infection in Peshawar. This case control study was conducted on three groups of patients who were investigated for HCV infection. Group I [78 Patients clinically and histological confirmed OLP were tested for HCV infection.Group II [78 Patients] control group seeking treatment for other mucosal lesions were screened for HCV infection. Group III [1809 patients] volunteers control group consisted of healthy persons who came to Khyber college of dentistry, Peshawar for dental treatment were also screened for HCV infection. In group I, 1[1.28%] patients were found HCV positive with age range of 30-65 years. In group II, 2 [2.86%] patients were HCV positive while in group III, 56[3.09%] patients were HCV positive. The weak association between OLP and HCV infection was seen in these patients. The result was not significant in the participants P>0.05. This study suggested that no clear relationship could be established between OLP and HCV infection in Peshawar