Macrophage colony stimulating factor and serum lipid profile in patients with aplastic anemia

ABSTRACT

The study was carried out on 22 patients with congenital aplastic anemia, 24 patients with acquired aplastic anemia and 20 patients with ITP in comparison to a control group of 15 healthy children. Estimation of MCSF and serum lipid profile was carried out in the patients. MCSF levels proved to be elevated while lipids were low among cases of aplastic anemia. However these levels failed to reach statistically significant values to justify their use as diagnostic or prognostic criteria in aplastic anemia. The two parameters did not show any relation to the severity of anemia or response to treatment. MCSF also proved to be elevated in patients with ITP