Renal involvement in children with varicella

ABSTRACT

The urine, blood urea, endogenous creatinine clearance, and plasma and urine osmolality were studied in 40 children with apparently uncomplicated varicella and 10 healthy reference children. The study has presented evidence for renal involvement in the course of varicella infection. Abnormal urinary findings were found in 17 children with this disease. Four cases with low ASO titers, had findings consistent with acute glomerulonephritis. The kidney function studies revealed mild reduction of glomerular filtration and impaired renal concentrating ability in children with varicella. These renal changes are apparently benign and transient, but should be considered in managing children with this disease